70 year old female with altered sensorium

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CASE PRESENTATION:

Patient came to casualty with chief complaints of 
Involuntary movements of B/L upper limbs and lower limbs since 1 day
Altered sensorium since 1 day

HOPI:
Pt was apparently asymptomatic 5 days ago and then she developed fever which is of high grade associated with chills and rigors and was diagnosed to have dengue and was treated for the same in a private hospital.Pt count 30k-35k-40k.
Pt also had involuntary movements of B/L upper limbs and lower limbs.Pt is agitated and decreased talking since morning 
No h/o tongue bite/uprolling of eye balls
No h/o Vomiting/involuntary micturition/Bowel movements 


Not a k/c/o DM ,HTN,TB,epilepsy and asthma 
Chronic smoker (chutta)since 30years,stopped 1 year back
Toddy drinker (on and off),stopped 20years back
H/O cataract surgery 1 year back

















At the time of admission 
Patient is in altered sensorium with her GCS being
E3V1M5(eye opening on calling,inappropriate sounds,localising pain)
Bp 160/100mmHg
PR 65bpm
Saturation 96%on room air(after 30 minutes after admission saturation 88% on room air,blood gas analysis was done and showed hypoxia and metabolic alkalosis 
RR-20 cpm
GRBS-157 mg/dl
Temp-97.5
Spo2-96 % on 6 lts O2
Neck stiffness was Present 
brudzinski sign was positive
Urea: 79mg/dL
Creat:1.6mg/dL
Na: 117mEq/L
K:3.5mEq/L
Cl:74mEq/L
Hb: 15.6gm/dL
TLC: 9700cells/cumm
Plt 78000cells/cumm
PT 24sec
INR 1.7
APTT 48sec
Urinary electrolytes 
UNa:191
Ucl:217
Uk:39.8
Serum osmolarity 251

O/E:
Pt is irritable
Temp-afebrile
BP- 130/80 mmHg 
PR-70 bpm
RR- 20 cpm
CVS-S1S2 +
RS-BAE +
P/A - soft,NT
CNS:
Pupils-
Right-sluggish reactive to light
Left-cataracr surgery- done reactive 
Neck rigidity +
Brudzinski' sign +
GCS-E2V2M5
CNS-
Power:   Couldn’t be elicited 
Moving all four limbs to pain

TONE

U/L.      Increased   Increased 
L/L.      Increased    Increased 

Tremors +
Involuntary movements +

Reflexes: Right.     Left. 

Biceps.      ++.          ++

Triceps.    +              ++

Supinator +                +

Knee.         ++.          +

Ankle        +                 +
Plantar-   M               M






















Provisional Diagnosis:
Altered sensorium secondary to? Hyponatremia? Meningoemceohalitis(viral dengue positive)
Metabolic alkalosis secondary to GI losses/hypokalemia

TREATMENT:

On 3/12/22

1)INJ. 3% NS @ 100 ml/hr
2)O2 supplementation to maintain saturation above 92
3)IVF @ 50 ml/hr
4)Ryles feed protein powder,milk 100 ml/4th hrly
    Water 100 ml 2nd hrly
5)INJ.VIT K 2amp
6)SYP POTCHLOR 10ml/RT/TID in 1 glass of water
7)INJ..DEXA 8 mg IV/TID
8)INJ.MONOCEF 2g IV/BD

On 4/12/22

1. 02 supplementation to maintain sat> 92%
2. Ryles feed-  milk with protein powder(100 ml 4th hrly)
- water 100 ml 2nd hrly
3.INJ.DEXA 8 MG/IV/TID(D2)
4.INJ.MONOCEF 2G/IV/BD(D2)
5.IVF NS@ 50 ML/HR IV CONTINUOUS INFUSION 
6.INJ.OPTINEURON 1AMP +  100 ML NS
7.VITALS ,GRBS MONITORING 4TH HRLY

On 5/12/22

1. 02 supplementation to maintain sat> 92%
2. Ryles feed-  milk with protein powder(100 ml 4th hrly)
- water 100 ml 2nd hrly
3.INJ.DEXA 8 MG/IV/TID(D2)
4.INJ.MONOCEF 2G/IV/BD(D2)
5.IVF NS@ 50 ML/HR IV CONTINUOUS INFUSION 
6.INJ.OPTINEURON 1AMP +  100 ML NS
7.Thrombophobe ointment 
8.VITALS ,GRBS MONITORING 4TH HRLY






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